NICHOLAS BRANDON works at AstraZeneca within the
Neuroscience Innovative Medicines Group. He has spent his career in
drug discovery with a strong interest in developing
phosphodiesterase inhibitors for neuropsychiatric disorders and
understanding the basic mechanisms of phosphodiesterase
function.

ANTHONY WEST is an Associate Professor in the Department
of Neuroscience at Rosalind Franklin University. He has studied PDE
function in the basal ganglia for over fifteen years, focusing on
neurochemical and electrophysiological changes induced by PDE
inhibitors in the healthy brain and in animal models of
Parkinson's disease and Huntington's disease.