As Joyce Novak's daughter, Marnie, completes medical school and looks ahead to a surgical internship, her wedding, and a future filled with promise, a breast cancer diagnosis throws Joyce's own future into doubt. Always the caregiver, Joyce feels uncomfortable in the patient role, especially with her husband and daughter. As she progresses through a daunting treatment regimen including a biopsy, lumpectomy, and radiation, she distracts herself by planning Marnie's wedding. When the sudden death of a young heroin addict in Marnie's care forces Marnie to come face-to-face with mortality and her professional inadequacies, she also realizes she must strike a new balance between her identity as a doctor and her role as a supportive daughter. At the same time, she struggles with the stark differences between her fiancé's family background and her own and comes to understand the importance of being with someone who shares her values and experiences. Amid this profound soul-searching, both Joyce and Marnie's futures change in ways they never would have expected.

When Joyce Novak is diagnosed with breast cancer, she and her daughter, Marnie-a medical student who is on the cusp of both beginning a surgical internship and getting married-mother and daughter are forced to face Joyce's mortality together, a journey that changes both their lives in surprising and profound ways.