"The Five Orange Pips" is a short story by Sir Arthur Conan Doyle, first published in The Strand Magazine in November 1891 and included in The Adventures of Sherlock Holmes. It follows a young man who seeks Holmes's help after members of his family receive mysterious letters containing five orange pips-shortly before dying under unexplained circumstances. As Holmes investigates, he uncovers connections to events and affiliations from the American South, revealing a case shaped by international intrigue and personal vengeance. The story is one of the few in which Holmes is unable to prevent a tragic outcome.