Saving Seraphina begins on a fateful spring afternoon in 1980, when Aster, a young mother suffering from post-partum psychosis takes her newborn daughter, Seraphina, to a Toronto subway station. A tragedy unfolds that brings together three strangers and forever alters the course of their lives: Borys, the young train driver; Daisy, an idealistic poet, who is on the platform with Aster; and Jane, Aster's teenaged sister. Saving Seraphina explores what it means to love and to grieve, but ultimately it uncovers how we are defined, not by our losses, but by the way we transcend them.